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  1. An institution, body, office or agency established by or based on the Treaty on European Union and the Treaties establishing the European Communities.

    All education and training facilities for people of different age groups.

    An intergovernmental organization having legal personality under public international law or a specialized agency established by such an international organization. An international organization, the majority of whose members are Member States or Associated Countries and whose main objective is to promote scientific and technological cooperation in Europe, is an International Organization of European Interest.

    A person with legal rights and obligations. Unlike a legal entity, a natural person does not have a legal act (e.g. association, limited liability company, etc.).

    An NPO is an institution or organization which, by virtue of its legal form, is not profit-oriented or which is required by law not to distribute profits to its shareholders or individual members. An NGO is a non-governmental, non-profit organization that does not represent business interests. Pursues a common purpose for the benefit of society.

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    A research institution is a legal entity established as a non-profit organization whose main objective is to conduct research or technological development. A college/university is a legal entity recognized by its national education system as a university or college or secondary school. It may be a public or private institution.

    A microenterprise, a small or medium-sized enterprise (business) as defined in EU Recommendation 2003/361. To qualify as an SME for EU funding, an enterprise must meet certain conditions, including (a) fewer than 250 employees and (b) an annual turnover not exceeding EUR 50 million and/or an annual balance sheet total not exceeding EUR 43 million. These ceilings apply only to the figures for individual companies.

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  1. Administration & Governance, Institutional Capacity & Cooperation 

    This topic focuses on strengthening governance, fostering institutional capacity, and enhancing cross-border cooperation. It includes promoting multilevel, transnational, and cross-border governance by designing and testing effective structures and mechanisms, as well as encouraging collaboration between public institutions on various themes. 

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    Tourism development is also central, with actions aimed at promoting natural assets, protecting and developing natural heritage, and increasing touristic appeal through the better use of cultural, natural, and historical heritage. It also covers the improvement of tourist services and products, the creation of ecotourism models, and the development of sustainable tourism strategies. 

    This topic focuses on the sustainable management, protection, and valorisation of natural resources and areas, such as habitats, geo parks, and protected zones. It also includes preserving and enhancing cultural and natural heritage, landscapes, and protecting marine environments. 

    Circular economy initiatives play a key role, with actions aimed at innovative waste management, ecological treatment techniques, and advanced recycling systems. Projects may focus on improving recycling technologies, organic waste recovery, and establishing repair and re-use networks. Additionally, pollution prevention and control efforts address ecological economy practices, marine litter reduction, and sustainable resource use. 

    This topic covers labour market development and employment, focusing on creating job opportunities, optimizing existing jobs, and addressing academic (un)employment and job mobility. It also includes attracting a skilled workforce and improving working conditions for various groups. 

    Strengthening small and medium-sized enterprises (SMEs) and boosting entrepreneurship are key priorities. This includes enhancing SME capacities, supporting social entrepreneurship, and promoting innovative business models. Activities may focus on creating advisory systems for start-ups, spin-offs, and incubators, fostering business networks, and improving the competitiveness of SMEs through knowledge and technology transfer, digital transformation, and sustainable business practices. 

    This topic focuses on fostering community integration and strengthening a common identity by promoting social cohesion, positive relations, and the development of shared spaces and services. It supports initiatives that enhance intercultural understanding and cooperation between different societal groups. 

    Demographic change and migration address key societal challenges, such as an aging population, active aging, and silver economy strategies. It also includes adapting public services and infrastructure to demographic shifts, tackling social and spatial segregation, and addressing brain drain. Migration-related actions cover policy development, strategic planning, and the integration of migrants to create inclusive and resilient communities. 

    All projects where ICT has a significant role, including tailor-made ICT solutions in different fields, as well as digital innovation hubs, open data, Internet of Things; ICT access and connecting (remote) areas with digital infrastructure and services; services and applications for citizens (e-health, e-government, e-learning, e-inclusion, etc.); services and applications for companies (e-commerce, networking, digital transformation, etc.).

    This is about the mitigation and management of risks and disasters, and the anticipation and response capacity towards the actors regarding specific risks and management of natural disasters, for example, prevention of flood and drought hazards, forest fire, strong weather conditions, etc.. It is also about risk assessment and safety.

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    This topic focuses on promoting equal rights and strengthening social inclusion, particularly for marginalized and vulnerable groups. It covers activities enhancing the capacity and participation of children, young people, women, elderly people, and socially excluded groups. Activities can address the creation of inclusive infrastructure, improving access and opportunities for people with disabilities, and fostering social cohesion through innovative care services. It also includes initiatives supporting victims of gender-based violence, promoting human rights, and developing policies and tools for social integration and equal participation in society. 

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    This area focuses on strengthening justice, safety, and security through cross-border cooperation and institutional capacity-building. It includes initiatives aimed at improving the efficiency and effectiveness of police, fire, and rescue services, enhancing civil protection systems, and rapid response capabilities for emergencies like chemical, biological, radiological, and nuclear incidents. Activities also target the prevention and combatting of organized crime, drug-related crimes, and human trafficking, as well as ensuring secure and efficient border management. Furthermore, it covers initiatives promoting the protection of citizens, community safety, and the development of innovative security services and technologies. 

    This area focuses on the development and improvement of transport and mobility systems, covering all modes of transport, including urban mobility and public transportation. Actions aiming at improving transport connections through traffic and transport planning, rehabilitation and modernisation of infrastructure, better connectivity, and enhanced accessibility. Projects promoting multimodal transport and logistics, optimising intermodal transport chains, offering sustainable and efficient logistics solutions, and developing multimodal mobility strategies. Also, initiatives establishing cooperation among logistic centres and providing access to clean, efficient, and multimodal transport corridors and hubs. 

    Activities focusing on the sustainable development and strategic planning of urban, regional, and rural areas. This includes urban development such as city planning, urban renewal, and strengthening urban-rural links through climate adaptation, sustainable mobility, water efficiency, participatory processes, smart cities, and the regeneration of public urban spaces. Regional planning and development cover the implementation of regional policies and programmes, sustainable land use management plans, integrated regional action plans, spatial planning, and the efficient management of marine protected areas. Rural and peripheral development addresses the challenges of remote and sparsely populated areas by fostering rural community development, enhancing rural economies, improving access to remote regions, and promoting tailored policies for rural sustainability and growth. 

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Call key data

Genome of Europe

Funding Program

Digital Europe

Call number

DIGITAL-2023-CLOUD-AI-04-GENOME

deadlines

Opening
11.05.2023

Deadline
26.09.2023 17:00

Funding rate

50%

Call budget

€ 20,000,000.00

Estimated EU contribution per project

max. € 20,000,000.00

Link to the call

Link to the submission

Call content

short description

This action will support the implementation of the Genome of Europe (GoE) multi-country project and contribute to achieving the objectives and long-term ambition of the 1+Million Genomes (1+MG) initiative.

Call objectives

GoE aims to establish and launch a European reference genome database of genetic variation obtained by whole genome sequencing (WGS) for at least 500,000 citizens based on population-based national reference genome collections, collectively representative of the European population. GoE has the potential to foster break-through advances in research, innovation, disease prevention and healthcare delivery, widely spread across clinical disciplines, beyond current use cases (disease areas). Moreover, creation of a reference database will allow meaningful savings in healthcare systems as it will enable data imputation and enrichment of genotype information. A concerted genome sequencing effort is necessary to achieve a critical mass of WGS data across Europe. By fostering it, this action is expected to bring major efficiencies due to economies of scale and should enable all GoE countries to contribute with WGS data. It will also ensure consistent application of agreed common data requirements and quality measures across all national datasets, enabling the creation of a high-value European reference dataset.

The objective is also to support the initiative taking into account the potential creation of a European Digital Infrastructure Consortium (EDIC).

Scope:

The focus of the action is on whole genome sequencing at clinical grade depth necessary for clinical application. This can be achieved by coordinated WGS sequencing expected to enable massive new data collection in all GoE countries. WGS data for the GoE must be generated following the 1+MG Trust Framework that brings together a set of minimal recommendations to enable secure cross-border access to genomic data in Europe, in particular as regards ethical and legal aspects, data standards, data quality and technical inter-operability. To this end, sequencing specifications should follow the available 1+MG guidance and align closely with that initiative.

The biological samples needed to generate the data, i.e., to sequence the genomes, can either originate from existing population-based cohorts and national biobanks, or be collected from participants recruited specifically for the national and European GoE reference databases. The participants will be selected at the national level to be representative of the respective population, including a contribution of relevant minorities. To ensure uniform approach, the exact inclusion and selection principles need to be agreed at the European GoE level.

In parallel to data generating activities (WGS sequencing), the architecture, hardware and software necessary to aggregate national reference databases into a European reference database (The Genome of Europe) need to be designed, developed and implemented in cooperation with the Genomic Data Infrastructure (GDI) project. As well as newly generated GoE data, this should ensure effective integration of available national population-based WGS collections established before or independently of the GoE. The GoE database must be interoperable with and accessible through the 1+MG data infrastructure and equally aligned with the European Health Data Space (EHDS), in particular the infrastructure for secondary use of health data (HealthData@EU).

For data security reasons, sample transport, all WGS activities and genomic data transfer and storage must take place within the territory of eligible countries.

The GoE project forms an integral part of 1+MG and GoE data will be accessible via the European federated genomics data infrastructure (GDI) deployed under the Digital Europe topic DIGITAL-2021-CLOUD-AI-01-FEI-DS-GENOMICS. Besides Digital Europe’s Data Spaces, the topic is also synergetic with the RRF support for the GoE multi-country project as stipulated in the national recovery and resilience plans of several Member States. Cooperation with other relevant European initiatives, and due consideration of other projects and infrastructures, for example those funded under the Horizon 2020 and Horizon Europe research and innovation programmes and the EU4Health Programme (e.g. Genomics for Public Health), will be strongly recommended to build on and bring forward their results as well as to ensure a good use of synergies and complementarities.

The awarded project will use, in so far as possible, the smart cloud-to-edge middleware platform Simpl, and have to work in partnership with the Data Spaces Support Centre deployed under the first W in order to ensure alignment with the rest of the ecosystem of data spaces implemented with the support of Digital Europe Programme. The joint work will target the definition of:

  • the data space reference architecture, building blocks and common toolboxes;
  • the common standards, including semantic standards and interoperability protocols, both domain-specific and crosscutting;
  • The data governance models, business models and strategies for running data spaces.

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Expected results

  • Joint or coordinated sequencing (WGS), as described under Scope.
  • New WGS data for a large number of representative European citizens, to be further specified in the call document, generated in accordance with the guidance, specifications and standards agreed within 1+MG (1+MG Trust Framework).
  • Integration of eligible population-based WGS data generated independently of the GoE and made available to the project.
  • The Genome of Europe federated reference database established and accessible through the federated European genomic data infrastructure and the European Health Data Space (EHDS) infrastructure for secondary use of health data (HealthData@EU).

Eligibility Criteria

Regions / countries for funding

EU Member States, Overseas Countries and Territories (OCT)
Moldova (Moldova), Albania (Shqipëria), Iceland (Ísland), Kosovo (Kosova/Kosovë / Косово), Liechtenstein, Montenegro (Црна Гора), North Macedonia (Северна Македонија), Norway (Norge), Serbia (Srbija/Сpбија), Türkiye, Ukraine (Україна)

eligible entities

Education and training institution, Natural Person, Non-Profit Organisation (NPO) / Non-Governmental Organisation (NGO), Other, Private institution, incl. private company (private for profit), Public Body (national, regional and local; incl. EGTCs), Research Institution incl. University, Small and medium-sized enterprise (SME)

Mandatory partnership

Yes

Project Partnership

To be eligible for funding, applicants must be:

  • legal entities (public or private bodies)
  • established in one of the eligible countries:
    • EU Member States (including overseas countries and territories (OCTs))
    • listed EEA countries and countries associated to the Digital Europe Programme or countries which are in ongoing negotiations for an association agreement and where the agreement enters into force before grant signature (together ‘DEP associated countries’, see list of participating countries)
Proposals must be submitted by a consortium of at least 5 applicants (beneficiaries; not affiliated entities) and which complies with the following conditions:
  • minimum 5 independent entities (beneficiaries; not affiliated entities) from 5 different eligible countries

Specific cases:

Natural persons are NOT eligible (with the exception of self-employed persons, i.e. sole traders, where the company does not have legal personality separate from that of the natural person).

International organisations — International organisations are not eligible, unless they are International organisations of European Interest within the meaning of Article 2 of the Digital Europe Regulation (i.e. international organisations the majority of whose members are Member States or whose headquarters are in a Member State).

EU bodies — EU bodies (with the exception of the European Commission Joint Research Centre) can NOT be part of the consortium.

Additional information

Topics

Digitalisation, Digital Society, ICT, 
Health, Social Services, Sports

Relevance for EU Macro-Region

EUSAIR - EU Strategy for the Adriatic and Ionian Region, EUSALP - EU Strategy for the Alpine Space, EUSBSR - EU Strategy for the Baltic Sea Region, EUSDR - EU Strategy for the Danube Region

UN Sustainable Development Goals (UN-SDGs)

project duration

42 months

Additional Information

Proposals must be submitted electronically via the Funding & Tenders Portal Electronic Submission System (accessible via the Topic page in the Search Funding & Tenders section. Paper submissions are NOT possible.

Proposals must be complete and contain all the requested information and all required annexes and supporting documents:

  • Application Form Part A — contains administrative information about the participants (future coordinator, beneficiaries and affiliated entities) and the summarised budget for the project (to be filled in directly online)
  • Application Form Part B — contains the technical description of the project (to be downloaded from the Portal Submission System, completed and then assembled and re-uploaded)
  • Mandatory annexes and supporting documents (to be uploaded):
    • detailed budget table/calculator: not applicable
    • CVs of core project team: not applicable
    • activity reports of last year: not applicable
    • list of previous projects (key projects for the last 4 years, template available in part B)
    • ownership control declarations

Proposals are limited to maximum 70 pages (Part B).

Contact

European Commission, Directorate-General for Communications Networks, Content and Technology
Website

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